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How to give a testosterone intramuscular (im) injection what is an intramuscular injection? an intramuscular injection, (illustration on right) delivers medication deep into the muscle tissue. This allows the medication to be quickly absorbed into the bloodstream. Testosterone injections are given into the muscles, therefore, a testosterone injection is known as an intramuscular injection, or im injection. Im injections are easy to self-administer, and relatively safe and pain-free, once you know all of the steps and procedures to properly administer testosterone injections. Testosterone injection done once a week causes spikes in the level of testosterone followed by lows. This can make you feel worse by the end of the end compared to your pre-trt stare. Later on, the dead zone gets broader, feeling no relief with testosterone injection. What are testosterone injections? a testosterone injection is one way of counteracting the side effects of hypogonadism (low testosterone). 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